Defining DMTs
Disease-modifying therapies (DMTs) are used to treat forms of relapsing multiple sclerosis (RMS). If you’re talking to your doctor about options, remember to ask how each is administered, how they work within the body, and about clinical study results, too.
A given DMT may have a different impact on one patient versus another. In some cases, DMTs have been shown to reduce relapses and MRI activity, and slow disability progression.
How DMTs work
in the body
Each DMT has a specific way of working to help manage RMS. This is called a mechanism of
action—also known as MOA. These MOAs may include:
- Targeting the immune system, primarily the T cells or B cells.
- Altering the response of the immune system.
- Regulating overactive immune cells.
- Blocking movement of immune cells into the brain.
- Stopping overactive immune cells from proliferating.
How DMTs are taken
Orally
Oral treatments are DMTs in the form of a tablet or capsule that have a more frequent dosing schedule than infusion or injectable therapies.
By infusion
Infusion treatments are delivered intravenously (IV) directly into the vein. They are given less frequently than injectable or oral DMTs, though the course of treatment will vary from drug to drug.
By injection
DMTs are available for self-administration. Some are injections under the skin, while others are for injection into a muscle.
Researching
your options
When it comes to finding treatment for RMS, every patient is different. Educating yourself on the options available can go a long way toward finding a treatment that works for you. Some resources that will allow you to do your own research include:
- Disease foundation websites
- Individual product Prescribing Information and/or Medication Guide
- Talk with your healthcare provider and ask for their recommendation on any journal articles you can refer to for more information
- Expand your support network and find helpful RMS organizations. Start here!
Start exploring
If there’s one way to find the best treatment for you, it’s exploring your options. Learn more about two options you might not have considered yet.
See an Oral Option See an Infusion OptionPatient Portrayal
From the Nurses' Station
It’s normal to feel overwhelmed by all of these decisions. Do your research, but also ask your healthcare provider for recommendations. There is no such thing as a “dumb question” when it comes to your health.
See Doctor Discussion Guide
Next up: Goal setting & financial planning
Click ahead to learn about the importance of setting treatment goals and planning ahead financially.
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