

Getting Down to the Basics
If you've ever heard the words, "You have RMS," you might remember immediately wanting to learn all you could about the disease. Whether you're just beginning your search for information or you're looking for a quick refresh of relapsing multiple sclerosis (RMS) facts, we're here to help.
Top RMS Q&As
A healthcare provider will evaluate your medical history and results from neurological exams and lab tests. This helps rule out other diseases and confirm an RMS diagnosis. Although there are no specific symptoms, physical findings or laboratory tests that can indicate RMS on their own, your doctor can look at your medical history and your background to determine if you meet the diagnostic criteria for RMS.
Unfortunately, the way you feel isn't a telltale sign of how stable your RMS is. Even if you’re not experiencing symptoms, the disease could be causing damage. The key is treating RMS early and monitoring progression.
RMS causes damage to your central nervous system (CNS) and slows the signals moving along your nerves. This results in a range of symptoms, including relapses, which are intense attacks of symptoms.
Damage to the CNS can build up, causing symptoms and worsening disability.
That’s why starting treatment early is critical for preserving brain volume, altering the disease course, and minimizing damage to the central nervous system.
Pseudo-relapses are short-lived RMS symptoms that can be triggered by outside factors like heat or stress. They don’t usually result in permanent damage, and they go away once their causes are out of the picture.

MS Doesn’t Discriminate
More than 2.3 million people worldwide and nearly 1 million in the United States are living with MS. And while it doesn’t discriminate, experts have noticed that gender, age, race, genetics, and geographic location may be linked to MS.
Patient Portrayal
The different types of MS
While we can’t predict how an individual's RMS will progress, there are 3 basic disease courses, or "types," that healthcare providers use to diagnose and treat their patients. The types are based on how far the disease has progressed in patients.
Of all MS types, relapsing-remitting MS (RRMS) is the most common. About 85% of people with MS are initially diagnosed with RRMS because there are clear signs of relapses or flare-ups that result in episodes of intense worsening of neurologic function. These relapses are followed by periods when symptoms partially or completely go away (remissions).
Quick Facts
- Most people with RRMS are diagnosed in their 20s and 30s.
- Women are affected 2 to 3 times as often as men.
- The most common symptoms of RRMS are: fatigue, numbness, vision problems, spasticity or stiffness, bowel and bladder problems, and problems with cognition.
- Transition from RRMS to secondary progressive MS (SPMS) generally happens after living with RRMS for at least 10 years.
Following an initial period of RRMS, some people develop secondary progressive MS (SPMS). This type is characterized by worsening symptoms and disability. It’s also less common to have periods of remission and relapse.
Quick Facts
- Without treatment, about 50% of people with RRMS go on to develop SPMS within 10 years, and 90% transition within 25 years.
- The speed of progression in SPMS varies significantly from person to person.
- The more you can describe your symptoms throughout the course of your disease, the better. Knowing how your symptoms change over time can help you and your doctor discuss treatment options and expected outcomes. Check out our doctor discussion guide for tips on how to keep conversations productive.
In this type, MS progresses slowly yet steadily from the time of onset. Patients with primary progressive MS (PPMS) experience a continuous worsening of their condition, but there can be variations in the rate of progression over time—as well as possible minor improvements and occasional plateaus in symptom progression.
Quick Facts
- About 15% of people living with MS are diagnosed with this type of MS.
- The number of women and men affected by PPMS is nearly equal.
- The average age of onset is almost a decade later in PPMS than in RMS.
- People with PPMS tend to experience more problems with walking.
If your MS is active, you can talk to your doctor about starting a disease-modifying therapy to reduce the risk of relapse.
From the Nurses' Station
Knowing which questions to ask and what type of information your doctor is looking for can help you get the most out of your doctor’s appointment.
Get tips on how to talk to your doctor.
Next Up: Understanding the impact of RMS
Knowing how RMS affects the body can help you better understand the condition and its symptoms.
Read OnKeeping tabs on RMS symptoms
When you communicate the ins and outs of your symptoms, you and your healthcare team can determine how to best manage them.
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